摘要
目的评价肝癌用三维适形放射治疗的疗效。方法对25例肝癌患者采用三维适形放射治疗，原发性肝癌16例，转移性肝癌9例；7例曾行1。2次介入治疗。肿瘤体积2．91～685．9cm^3，平均125．25cm^3，中位体积14．05cm^3。设3—5个共面等中心照射野，80％。90％的等剂量线包绕PTV，靶区包括肿瘤边缘外0．5～1．5cm，用6MV—X线照射，总量为DT43．2—54Gy，2．25—3．6Gy／F，每周5次，放疗结束后1-2个月复查CT。结果本组25例，CR5例（20％），PR14例（56％），SD5例（20％），PD1例（4％），有效率CR＋PR为76％。结论三维适形放射治疗适用于肝癌的治疗，不良反应小，效果明显，但制订治疗计划时应充分考虑放射性肝病的发生概率。
Objective To evaluate the effects of three-dlmensional conformal radiation therapy on liver carcinoma. Methods Between August 2003 to January 2006,25 cases with liver carcinoma were treated with three-dimensional conformal. Ofall the cases 17 were men, 8 were women, mean age 53, range from 14 to 70. Of the 25 patients 16 were primary hepatic cancer, 9 were metastatic hepatic cancer. Among them 7 patients were treated with 1 -2 times of transcatheter arterial chemoembolization （TACE）. Irradiation ridded had 3- 5,80% -90% isodose line included PTV. The total radiation dose of 43.2 - 54 Gy,2.25 - 3.6 Gy/F,5F/W. For 3DCRT, radiation was given by 6MV-X. Results In all the patients, the overall response rate was 76%. 5（20% ） were complete response （CR）, 14（56% ） partial response （PR）, stable response （SD）, progressive response （PD）. Conclusions 3DCRT was feasible in the treatment of liver carcinoma, with good immediate tumor response, and milder toxicity.
出处
《肿瘤基础与临床》
2006年第6期497-498,共2页
journal of basic and clinical oncology
关键词
肝脏肿瘤
放射疗法
适形
liver neoplasms
radiotherapy, conformal
