摘要
用ＥＬＩＳＡ方法对７８例肾小球疾病患儿做尿视黄醇结合蛋白（ＲＢＰ），β＿２一微球蛋白（β＿２一ＭＧ）及Ｎ一乙酰一β一Ｄ一氨基葡萄糖苷酶（ＮＡＧ）检测，并与８５例健康儿童相比较。结果发现：肾小球疾病组尿ＲＢＰ值急性期显著高于对照组（Ｐ＜０．０１）；缓解期与对照组结果相接近（Ｐ＞０．０５）．说明原发性肾小球疾病患儿确有不同程度肾小管功能受损；尿ＲＢＰ值的改变不仅能反映肾小管功能受损程度及反映病情转归，而且比β＿２一ＭＧ，ＮＡＧ更敏感。
Enzvme- linked immunosorbent assay(ELISA)was use to assay urinarv retinol-binding protein(RBP),β_2-microglobulin(β_2-MG)and N-acetyl-B-D-glucosaminidase(NAG )in 78 glomerulopathy child patients,who were compared with 85 healthy children.The result in-dicated that RBP concentration was significantly higher(P<0.01)in glomerulopathy groupthan in control group during the acute stage,but was close to that of control group during thescothing stage, This suggested that various degrees of renal tubular function injury did exist inchildren with glomerulopathy.More sensitive than β_2-MG and NAG,RBP concentration pre-dicted not only the state of injury but also the ongoing of the disease.
出处
《昆明医学院学报》
1996年第3期51-53,69,共4页
Journal of Kunming Medical College
