摘要
目的:观察雷贝拉唑治疗胃食管反流病的临床疗效。方法:将60例胃食管反流病患者随机分为2组,雷贝拉唑组30例,服用雷贝拉唑10 mg,qd;对照组服用雷尼替丁150 mg,bid,早晚服用。疗程均为4周。结果:雷贝拉唑治疗组临床症状改善明显优于对照组,并明显改善内镜下食管炎分级,且不良反应少。结论:雷贝拉唑治疗胃食管反流病疗效显著。
Objective：To assess therapeutic effects of rabeprazole in patients with gastroesophageal reflux disease（GERD）. Methods：Sixty patients with GERD were randomly received rabeprazole 10 mg, qd, or ranitidine 150mg, bid, for 4 weeks. Results ： The general GERD symptoms and inflammation were improved more significantly in rabeprazole group than in ranitidine group. Furthermore,rabeprazoletreated patients experienced better prognosis of the oesophagitis classification under endoscope and few adverse reactions. Conclusiou：Rabeprazole has significant efficacy for GERD.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2006年第21期1876-1877,共2页
Chinese Journal of New Drugs
关键词
雷贝拉唑
胃食管反流病
食管分级
rabeprazole
gastroesophageal reflux disease
oesophagitis classfication
