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精神分裂症的遗传学研究

The Genetic Research of Schizophrenia
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摘要 目的:探讨精神分裂症与遗传学的关系.方法:随机抽取门诊和住院确诊为精神分裂症的100份病例,将其一级亲属的患病状况进行登记.以性别、年龄、人数与患者相同的健康人群一级亲属作为对照.计算精神分裂症的遗传度.结果:17~40岁发病者占73%.因此可将此年龄段视为精神分裂症患病的危险年龄,精神分裂症的遗传度为70.85%.结论:精神分裂症的易感性和家族聚集性主要是由遗传因素决定的,但环境因素对精神分裂症的发病也有一定的影响,属于多基因道传. Objective : To study the relationship between schizophrenia and genetics. Methods :100 cases with schizophrenia by clinic and hospital diagnosis were collected randomly, Register the patient hood of their first-degree relatives and make the ones of healthy population which had the same gender,age and numbers in control, then calculate the heritability of schizophrenia. Results: Patients aged 17-40 is 73 %. so this age group was regarded as risk stage of schizophrenic patients.the heritability of schizophrenia is 70. 85 %. Conclusion.. Schizophrenic susceptibility and family accumulation were mainly determined by genetic factors, however environmental factors also had some influence on the cause of schizophrenia. The schizophrenia is polygenic inheritance.
作者 王学民
出处 《荆门职业技术学院学报》 2006年第6期53-54,共2页 Journal of Jingmen Technical College
关键词 精神分裂症 遗传学 schizophrenia genetics
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  • 1江三多.一个估计阈值模式中各级亲属预期发病率的公式[J]遗传学报,1986(06). 被引量:1
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