摘要
目的探讨肝炎后肝硬变肝脏体积变化与其病变严重程度间的关系。方法采用16层螺旋CT对111例正常人及74例肝炎后肝硬变患者行容积扫描并得到肝脏体积。采用直线相关和回归方法研究正常人群肝脏体积与其身高、体重和体表面积的关系,得出相应回归方程作为成人标准肝体积公式。求出肝硬变患者肝脏体积指数及体积变化率,分析其与肝功能Child分级的关系。结果正常成人肝脏平均体积为(1225.15±216.23)cm3,与其身高、体重和体表面积均呈正相关。回归方程:肝脏体积(cm3)=876.02×体表面积(m2)-297.17或肝脏体积(cm3)=12.712×体重(kg)+450.44。肝硬变患者中Child A、B及C级全肝体积分别为(1077.77±347.01)cm3、(1016.35±348.60)cm3和(805.73±208.85)cm3,体积指数分别为0.87±0.26、0.83±0.26和0.67±0.17,肝脏体积变化率分别为(12.36±26.12)%、(16.82±26.29)%和(32.98±16.78)%,Child C级患者全肝体积及体积指数明显小于Child A、B级者(P<0.05),体积变化率明显高于Child A、B级(P<0.05)。结论16层螺旋CT体积测量结合成人标准肝体积公式可以定量评价病肝体积变化,肝硬变肝脏体积变化与疾病严重程度密切相关。
Objective To explore the correlation between liver volume variation of posthepatitic cirrhosis patients and the severity of the disease. Methods One hundred and eleven patients with normal livers and 74 posthepatitic cirrhosis patients underwent volume CT scan. The relation between normal liver volume and body height, body weight and body surface area was studied by linear regression and correlation method, the standard liver volume equation was deduced. The change ratio of liver volume in cirrhotic patients was calculated and compared with Child classification. Results The mean normal liver volume of Chinese adults was （1 225.15±216.23） cms , there was a positive correlation between liver volume and body height, body weight [liver volume （cms） = 12. 712 × body weight （kg） ＋450.44] and body surface area [liver volume （cms ） = 876.02 × body surface area （m^2 ） - 297.17]. The mean liver volume of Child A, BandC patients were （1 077.77±347.01） cms, （1 016.35±348.60） cms and （805.73± 208.85） cms respectively. The liver volume and liver volume index was significantly smaller in Child C patients than those in Chiid A and B patients （P〈0.05） ;while liver volume change ratio was higher in Child C patients （P〈 0.05）. Conclusion Liver volume variation of cirrhotic patients can be quantitatively assessed by 16 slices helical CT volume measurement and standard liver volume equation. The change of the liver volume is correlated with the severity of liver cirrhosis.
出处
《中国普外基础与临床杂志》
CAS
2006年第6期729-732,共4页
Chinese Journal of Bases and Clinics In General Surgery
关键词
肝硬变
体积测量
CHILD分级
16层螺旋CT
Liver cirrhosis Volume measurement Child classification Sixteen slices helical computed tomograph
