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胶原酶溶解术治疗腰椎间盘突出症疗效分析

Outcome Analysis of The Treatment for Lumbar Intervertebral Dise Herniation with Collagenase Chemolysis
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摘要 目的:评价胶原酶溶解术的近、中、远期疗效,分析机理、适应症等与疗效的关系。材料与方法:按统一的适应症选择标准、治疗方法,对行胶原酶溶解术资料完整的腰椎间盘突出症的最佳适应症1279例进行复诊、书信、电话等方式随访观察,随访时间和例数分别为;0.5~1年(近期)105例,2~4年(中期)593例,6~8年(远期)581例,按统一的疗效标准评价胶原酶溶解术的近、中、远期疗效。结果:取最佳适应症近期、中期、远期优良率分别为96.1%、85.4%、84.8%。结论:在最佳适应症范围内,胶原酶溶解术是腰椎间盘突出症的一种有效的微创治疗方法。 Purpose: To evaluate the early and medium- term and long- term therapeutic effect of collagenase chemolysis and analyse fire relationship between therapeutic effect and indication, mechanism. Materials and Methods: According to uniform diagnosis criterion and therapeutic method, 1279 patients with lumbar intervertebral disc herniation who had integral data and received collagenase chemolysis were follwoed (by return visit, letter of telephone et al). Following time and case number: 0.5 - 1 year (early) 105 case. 2 - 4 year (medium term ) 593 cases. 6 - 8 year (long- term ) 581 cases. The early and medium-term and long- term therapeutic effects of coUagenase chemolysis were evaluated with uniform therapeutic effect criterion. Results: The effective rate of the early and medium term and long- term of the best of all indication were 96.1%. 85.4%. 84.8% regpeetively. Conclusion: Within the best of all indicatious, the collagenase chemolysis is a effective and minimal invasive treaunent for lumbar intervertebral disc hernially.
出处 《现代医用影像学》 2006年第5期230-232,227,共4页 Modern Medical Imageology
关键词 胶原酶 腰椎间盘突出症 疗效 随访 Collagenase Lumbar intervertebral dise herniation Therapeutic effect Following
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