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川芎嗪治疗小儿原发性肾病综合征近期疗效观察 被引量:4

OBSERVATIONS ON THE SHORT TERM CURATIVE EFFECTS OF PRIMARY NEPHROTIC SYNDROME OF CHILDREN TREATED BY LIGUSTRAZINE
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摘要 肾病综合征(NS)高凝状态的治疗,传统多采用肝素,但副作用较多。为了寻找有效、副作用少的药物,我们选用活血化瘀中药川芎嗪对NS高凝状态的14例住院患儿治疗一月,并另选14例作为肝素对照组。发现川芎嗪组治疗前后血纤维蛋白原、血小板聚集率、尿蛋白、胆固醇、尿素氮、肌酐、血沉均明显下降,且与肝素组治疗前后改变无显者性差别。表明川芎嗪对肾病综合征高凝状态的治疗效果肯定,具有安全、有效、副作用少。 The patients with nephrotic syndrome always have blood hypercoagulability which has become an important factor of imfluencing the treatent and pyognosis of the disease.The heparin traditionaly was used to treat hypercoagulability.But it has many side effects.In order to find an effective drug with less side effect 14 cases of children patients were treated by Ligustrazine,another 14 cases as hepari contrast group.The resuilt showed that the Ligustrazine had the same anticoagulability as heparin.
出处 《湖南中医学院学报》 1996年第3期18-21,共4页 Journal of Hunan College of Traditional Chinese Medicine
关键词 肾病综合征 中医药疗法 儿童 Nephrotic syndrome/TCM therapy Blood coagulation/drug effects Ligustrazine/therepy apply Children Contast study
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