摘要
用单光子骨密度测定仪测定桡骨中下1/3处骨密度的方法已被公认,并作为成人外周骨测定的标准方法,但对于小婴儿尤其是新生儿因上肢较短小,加上哭闹扭动难于合作,给操作带来不便。国内外至今尚未见这方面的报导,更无小婴儿及新生儿的骨密度正常值。他们的下肢骨相对较长,含胫腓两根骨酪与上肢的尺桡骨相当,所测结果准确性高重复性好,可作为临床研究小婴儿及新生儿骨代谢性疾病的良好诊断方法。同时我们还测定了大鼠的胫股骨骨密度,及进行了X线照片双波长仪扫描,而后经病理切片计算骨小梁数目,最后将胫股骨用湿灰化法消化后测定其含钙量,将上述结果分别与该骨所测的骨密度进行比较证明骨密度测定结果与这些结果均有很好的相关性(r值达0.88～0.98),进一步证明了小婴儿下肢骨密度测量方法的可靠性,及小块骨骼骨密度测量方法的建立也有助于临床科研及临床病理诊断。
It is generally acknowledged that bone miner density (BMD) measurement at the spot of distal 1/3 radius was completed with singlephoton absorptiometry and used as a standard method on measuring adult peripheral bone BMD, but this measurement is not suitable for infants especially newborns because of their shorter radius and uncollaboration. At present, there are not BMD normal value in infants and newborns. Their lower limbs were measured in this paper because their lower limbs with longer tibia and fibula are corresponded to their radius and ulna, the measured results are precise and repeatable. So this method has provided a good diagnosis means for infant and newborn's bone metabolic diseases in clinical, study. Simultaneously, BMD and X-ray examination of tibia and femur in SD rats were performed and then pathologic sections for counting the number of bone trabecula were examined. The tibia and femar bones were dealt with chemical for measuring Caw amount. The BMD value was correlated with above every item respectively and it confirmed that there was a good correlation(r = 0. 88-0. 89). This results demonstrated the reliability of BMD measurement in infant's lower limbs and the method for measuring BMD in a little piece of bone was contributed to clinical scienitifi study and pathological diagnosis.
出处
《影像诊断与介入放射学》
1996年第4期207-208,共2页
Diagnostic Imaging & Interventional Radiology
