摘要
７４例经病理学证实的小细胞肺癌，局限期３５例，广泛期３９例，均为初治病例。主要以ＡＣＯ、ＣＥ、ＡＯＥ、ＣＯＭＥ和ＣＯＰ方案治疗，其中ＡＣＯ方案有效率７５％，ＣＥ方案有效率８４％，ＡＯＥ方案有效率１００％，ＣＯＭＥ方案有效率８５％，ＣＯＰ方案有效率５０％，其它方案有效率５５％。结果在明，含ＡＤＭ、ＣＢＰ和ＶＰ－１６的联合方案优于其它方案（Ｐ＜０．０５）。毒副反应主要是胃肠道反应和骨髓抑制。
Seventy-four patients with histologically confirmed small cell lung cancer were treated with ACO, CE, AOE,COME and COP regimens. There were 35 limited-diseases and 39 extensive-diseases. All patients were initial treatment. Response rate was 75% with ACOregimen, 84% with CE regimen, 100% with AOE regimen, 85% withCOME,50% with COP regimen, and 55% with other regimens. Our data show the regimens contained doxorubicin,carboplatin and etoposide are superior to other regimens (P <0. 05). The major toxic effects were gastrointesrtinal symptoms and myelosuppression.
出处
《河北医学》
CAS
1996年第4期317-318,共2页
Hebei Medicine
关键词
小细胞肺癌
药物疗法
Small cell lung cancer
Chemotherapy
