摘要
目的:了解山东沿海地区人群当前血脂水平及高脂血症患病率。方法:采用随机、分层、整群抽样的方法,入户调查青岛、烟台、威海、日照、东营长期居住居民5 003名,均居住5年以上,年龄20～80岁。生化指标采用酶法及全自动生化分析仪。结果:①本次计划调查5 500名,实际调查5 003名,应答率为91％。其中男性2 395名,占47．9％;女性2 608名,占52．1％。②山东沿海地区血脂水平:与男性同年龄组比较,血清总胆固醇(TC)水平除20～和50～年龄组外,其余各组均有显著性差异(P<0．05～0．01);血清甘油三酯(TG)水平除50～年龄组外,其余各组均有极显著性差异(P <0．01);血清低密度脂蛋白胆固醇(LDL-C)水平仅30～、40～年龄组有显著性差异(P<0．05);血清高密度脂蛋白胆固醇(HDL-C)水平仅20～、30～、40～年龄组有显著性差异(P<0．05);男女间血脂总体水平比较均有极显著性差异(P<0．01)。③不同地区城乡血脂水平:与同地区同性别农村人群比较,血清TC水平男性青岛、威海、东营城市居民高于农村居民,有显著性差异(P<0．05);女性日照、青岛、东营城市居民高于农村居民,有显著性差异(P<0．05)。血清TG水平男性、女性日照、烟台、青岛、威海、东营城市居民均高于农村居民,均有显著性差异(P<0．05～0．01)。血清LDL-C水平男性威海、东营城市居民高于农村居民,有显著性差异(P<0．05);女性仅青岛城市居民高于农村居民,有显著性差异(P<0．05)。血清HDL-C水平仅男性青岛城市居民低于农村居民,有显著性差异(P<0．05)。④调查人群中TC≥5．72 mmol／L者为11．6％,按照2000年山东人口标化率为11．0％;TG≥1．70 mmol／L者为19．4％,标化率为18．6％。HDL-C≤0．91 mmol／L者为16．2％,标化率为15．7％。LDL-C≥3．64 mmol／L者为13．7％,标化率为13．2％。结论:随着居民生活水平的提高,平均血脂水平有增高的趋�
Objective ： To investigate the level of serum lipids and the prevalence of hyperlipidemia among residents aged 20-80 years in Shandong coastal area.
Methods： A random, stratified cluster sampling study was conducted. 5003 dwellers in Qingdao, Yantai, Weihai, Rizhao, Dongying were examined. The serum uric acid was detected with uricoxidase method, and other biochemical indexes were obtained through enzyme method. All tests were done by automatic biochemical analysis device.
Results： The average levels of serum total cholesterol （TC）, triglyceride （TG）, high density lipoprotein cholesterol （HDL- C） and low density lipoprotein cholesterol （LDL-C） were 4. 97 ± 1. 16, 1.29 ± 1.23, 1.36 ±0. 35 and 2. 72 ±0. 87 mmol/L. TC level increased along with the increasing age, especially in women. TG level increased with age in females, and in males 〈 50 years. It was higher in males 〈 60 years and in females 〉 60 years. HDL-C level had no significant change according to age,and it is lower in men than in women. Significant differences in serum lipid level were found between different areas. TG〉 5.72 mmol/L was found in 11.6% of the subjects, TG 〉t 1.70 mmol/L in 19. 4% , HDL-G〈 0. 91 mmol/L in 16. 2%, and LDL-G〉3. 64 mmol/L in 13.7%.
Conclusion： The serum TC, TG, and LDL-C levels have an upward tendency in population of Shandong coastal areas. Health education and regular serum lipid tests should be carried out in order to reduce incidence rate of cardiovascular diseases.
出处
《中国循环杂志》
CSCD
北大核心
2006年第5期347-351,共5页
Chinese Circulation Journal
基金
本研究得到青岛市科技局攻关课题(03-1-NY-14-1)资助
关键词
血脂
流行病学
山东沿海
Serum lipid
Epidemiology
Shandong coastal area
