摘要
目的探讨冠状动脉病变患者血清C反应蛋白水平及其与冠状动脉病变严重程度的关系。方法采用胶乳增强免疫比浊法测定经冠状动脉造影证实的管腔直径狭窄>50%￣95%冠状动脉病变患者血清C反应蛋白水平,与年龄、性别相匹配的冠状动脉造影证实的非冠状动脉病变患者进行比较。结果冠状动脉病变患者血清C反应蛋白水平明显高于对照组(P<0.05),重度狭窄组血清c反应蛋白明显高于中度狭窄组(P<0.05)。结论冠状动脉病变患者血清C反应蛋白水平明显升高,可反映冠状动脉病变的严重程度。因此血清C反应蛋白水平可作为冠状动脉病变程度的参考指标之一。
Objective To explore the relationship between serum C-reactive protein （CRP） level and severity of coronary artery disease （CAD）. Methods Detected CRP concentrations in patients who underwent coronary angiography and were proved to be CAD with the severity scale of coronary artery stenosis ranging from 〉50% to 95% by latex-enhanced immunoturbidimetric assay. Compared CRP between these patients and the control group patients matching in gender and age who were proved not to be CAD by conorary angiography. Results The serum CRP concentrations were higher in the CAD patients than that in the control group（P〈0.05） and they were also higher in the severe stenosis patients than that in the moderate stenosis patients（P〈0.05）. Conclusion The level of CRP was elevated in patients with coronary artery disease and it reflected the severity of coronary artery stenosis. CRP may be one of the indexes to predict the severity of CAD.
出处
《中国现代医药杂志》
2006年第10期51-52,共2页
Modern Medicine Journal of China
