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缬沙坦联合胺碘酮防治阵发型房颤的作用研究

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摘要 目的 观察缬沙坦联合胺碘酮防治特发性阵发型房颤(IPAF)的作用.方法 选择我院2002~2004年140例IPAF患者随机分为A组(安慰剂)、B组(胺碘酮)、C组(缬沙坦)、D组(胺碘酮加缬沙坦),通过12导联同步心电图测定最大P波时限(Pmax)、P波离散度(Pd),观察缬沙坦对IPAF的疗效及对Pmax、Pd影响.结果 随访6个月,D组较A组Pmax、Pd及房颤发生的频率和持续时间均明显减少(P<0.05).4组患者治疗前、后左心房内径(LAD)、舒张末期面积(EDA)、舒张末期容量(EDV)间差异均无显著性意义(P>0.05).结论 缬沙坦联合胺碘酮可减少IPAF的Pmax、Pd及发作持续时间和频率而可用于防治IPAF.
出处 《实用心脑肺血管病杂志》 2006年第9期704-705,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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