摘要
目的用 SPECT 技术探讨脑出血患者治疗前后继发性缺血灶局部脑血流的变化及临床意义。方法 60例脑出血患者随机分为尼莫地平组与常规治疗组,在治疗前后用 SPECT 显像观察原发灶缺血体积、血肿周围及脑部其他区域的脑血流灌注减低区变化。结果尼莫地平组和常规治疗组治疗后原发灶缺血体积明显缩小,前者比后者更明显;原发灶及远隔部位缺血灶局部脑血流增加值尼莫地平组明显高于常规治疗组(P<0.01)。结论 SPECT 脑血流灌注显像可灵敏地反映治疗前后局部脑血流变化,可用于药物疗效评价。
Objective To explore the clinical value of SPECT perfusion imaging in brain ischemic injury due to cerebral hemorrhage before and after treatment.Methods Sixty cases of cerebral hemorrhage were randomly divided into nimodipine treated group and routine treated group.The volume of primary is- chemic focus,changes of regional cerebral blood perfusion around hematoma and other cerebral areas were observed by SPECT imaging.Results Volume of the primary focus was reduced apparently in both groups, but much more in nimodipine treated group(P<0.1).Also the regional cerebral blood flow in ischemic focus and remote areas increased much more in nimodipine treated group than routine treated group(P< 0.01).Conclusions Brain SPECT imaging can sensitively reflect the regional cerebral blood flow before and after treatment.Thereby,it is useful for therapeutic monitoring.
出处
《中华核医学杂志》
CAS
CSCD
北大核心
2006年第5期290-292,共3页
Chinese Journal of Nuclear Medicine
