摘要
原发性高血压患者细胞内ｐＨ值的测定及其临床意义陈绍良１徐祖玲２谢丹红３（１．甘肃省人民医院心内科，兰州７３００００２．兰州医学院第二附属医院７３００００３．广东省珠海市医疗中心５１９０００）ＣｌｉｎｉｃａｌＳｉｇｎｉｆｉｃａｎｃｅｏｆＩｎｔｒａｃｅｌ...
Aim\ To
determine the intracellular pH and calcium ion in patients with
essential hypertension.\ Methods\ Sixty cases of essential
hypertension was recruited to enroll the study.\ The lymphocytes of
the patients was isolated and washed with non HCO 3 washing water.\
Results\ It was demonstrated the pH in pretreated EH patients was
markedly lower than in controls, while [Ca 2+ ]i in EH patients
was higher.\ A negative correlationship between pHi and blood
pressure( r=-0 86,P <0 001) was demonstrated.\ Conclusion\ That
trans membrance proton transport(especially Ca 2+ /H +
exchange) might hold potential role in regulating vascular tone and
pHi in EH patients.
出处
《高血压杂志》
CSCD
1996年第4期262-263,共2页
Chinese Journal of Hypertension
关键词
原发性
高血压
细胞内PH值
细胞内游离钙
essential hypertension
transmembrane
proton transport
intracellular pH value
intracellular free calcium
