摘要
目的分析Graves病的常见死亡原因,提出相应的预防、诊疗方法,以降低Graves病死亡率。方法回顾性分析近5年21例Graves病死亡病例的临床资料。结果以Graves病为原发病死亡的患者共21例,其中男8例,女13例,年龄31￣65岁,并发症有:甲状腺危象4例,甲亢性心脏病17例,粒细胞缺乏症3例,脑梗死2例,周期性麻痹1例。死亡原因有:甲亢性心脏病、猝死10例(47.62%),甲状腺危象4例(19.05%),粒细胞缺乏症合并败血症3例(14.29%),合并糖尿病、肺结核致全身衰竭2例(9.52%),脑梗死1例(4.76%),肠系膜动脉栓塞伴肠坏死、感染性休克1例(4.76%)。结论甲亢性心脏病是Graves病的主要死亡原因。早期就诊治疗、减少Graves病并发症、避免感染及精神创伤、使用抗甲状腺药物期间监测血常规等,是降低Graves病死亡率的重要措施。
[Objective] To analyse the main death causes in Graves＇ disease and provide the prevention and treatment protocal. [Methods] The clinical data of 21 death cases caused by Graves＇ disease in the last period of 5-year were analyzed retrospectively. [Results] 21 death patients caused by Graves＇ disease, including 8 males and 13 females, whose age was from 31 to 65 years, were investigated. There are 4 cases with thyroid storm, 17 cases with hyperthyroid heart disease, 3 cases with agranulocytosis, 2 cases with cerebral brain infarction, and 1 case with periodic paralysis when admitted to the hospital. Death cause included hyperthyroid heart disease occured to sudden death 47.62% （10/21）, thyroid storm 19.05%（4/21）, agranulocytosis associated with sepsis 14.29%（3/21）, cachexia because of diabetes mellitus and pulmonary tuberculosis 9.52% （2/21）, cerebral infarction 4.76% （1/21）, mesentery artery embolism, intestines putrescence and infectious shock 4.76% （1/21）. [Conclusion] Hyperthroid heart diseases are the primary death cause of the patients caused by Graves＇ disease. It may be helpful to decrease the mortality in Graves＇ disease patients by early diagnosis and treatment, reducing complications, avoiding infection and spirit trauma and monitoring blood cell count in the period of follow-up.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2006年第19期3001-3003,共3页
China Journal of Modern Medicine
