摘要
目的了解泌尿系感染患者产超广谱β-内酰胺酶(ESBLs)大肠埃希菌株的感染情况及耐药性。方法采用纸片扩散法(K-B法),结果判断参照NCCLS标准进行。结果产ESBLs大肠埃希菌检出率为26.8%,住院患者与门诊患者检出率差异有显著性。产ESBLs大肠埃希菌对亚胺培南最敏感,对头孢哌酮/舒巴坦、呋喃妥因亦有一定的敏感率;产ESBLs菌株耐药性明显高于非产ESBLs菌株。结论基层医院亦应建立完善的ESBLs监测制度,指导临床合理应用抗生素。
Objective To stuty the infectious standard and resistance of ESBLs produced in Escherichia,coli isolated from urinary infections. Methods The bacterial susceptibility was tested by Kirby-Bauer（K-B） method as described in NCCLS. Results The positive rate of ESBLs-produced was 26.8%, and there were signi ficant difference among in-patients and out-patients. The sensitive rite of ESBLs producing Escherichia coli to imipenem was the most highest,There were some sensitive rate in cefoperazone-sulbactam and nitrofurantoin. The drug resistance of ESBLs Escherichia coli was more higher than the non-ESBLs ones. Conclusion The hospital in grass roots should set up the whole surveillance system to ESBLs. It is very important for clinic so as to choose antibiotic rationally.
出处
《实用医技杂志》
2006年第19期3347-3348,共2页
Journal of Practical Medical Techniques
