摘要
本实验目的是探索G IF接种在脑内进行中枢神经系统疾病基因治疗的可行性.方法是用适量的G IF-GFP融合蛋白腺病毒载体直接注入c57小鼠脑内,3天、7天、28天、60天后分别用显微镜观察脑切片,结果发现G IF-GFP融合蛋白在脑中有表达且安全稳定.实验结果表明利用G IF进行中枢神经系统疾病的基因治疗是可行的.
The aim of this experiment is to explore GIF inoculability＇s feasibility of gene treatment of nerve center syslem disease in the brain. The proper amount of GIF - GFP fusion protein adenovirus vector were directly injected into c57 mice＇s brain and the brain slices were made after 3 days, 7 days, 28 days and 60 days. As a result, we find that GIF ： GFP fusion protein express itself safely and steadily in the brain. The result shows that it is feasible to cure the disease of nerve center system using GIF.
出处
《商丘职业技术学院学报》
2006年第5期95-97,共3页
JOURNAL OF SHANGQIU POLYTECHNIC
