摘要
宫颈癌是威胁女性最主要的恶性肿瘤之一,近年来发病率不断上升,尤其是年轻化趋势现象(≤35岁)的出现引起了广大研究者的关注,而早期宫颈癌的治疗效果和5年生存率也位于恶性肿瘤的前列,这一特点使宫颈癌的筛查具有了非凡的意义。自多种筛查方法应用于临床以来,宫颈癌的发病率和死亡率都有显著改善。除传统的宫颈涂片细胞学检查以外,目前宫颈癌的筛查方法主要有:薄层液基细胞学检查、阴道镜检查、HPV-DNA检查和肉眼观察等。根据不同地区的经济条件和人群特征,这些筛查方式单独或联合使用对宫颈癌及癌前病变的检出均具有很大的临床意义。
Cervical cancer is one of the most common malignant tumor of women. Recently, its incidence has increased, especially, the trend of younger in average occurrence age （ ≤35 years old ） has attracted more attention of many researchers, while the therapeutic effect and 5-year survival rate for early stages of cervical cancer also place in front, this makes the screening of cervical cancer to be of most important significance, Because of application of several methods to screen cervical intraneoplasia（ CIN）, its incidence and mortality rate have decreased sharply. Except conventional cervical smear cytological examination, the main screening methods include thin layer liquidbased cytology （LBS）, colposcopy, HPV DNA detection with a second-generation hybridization assay （HC Ⅱ ） and visual inspection. According to different economy conditions and population features in different areas, single or combined application of these several methods is of important significance.
出处
《中国妇幼健康研究》
2006年第5期443-446,共4页
Chinese Journal of Woman and Child Health Research
