摘要
目的研究二极管发光器(LED)的多焦视网膜电图(mfERG)的一阶及二阶波形特点。设计前瞻性、非对照干预研究。研究对象18例(18眼)正常人。方法18眼随机分为两组分别作阴极射线管(CRT)及LED的mfERG检查。LED刺激时间分为1/10(1．7ms)、3/10(5ms)、5/10(8．3ms)、7/10(11．7ms)、10/10(16．7ms)5种。主要指标mfERG总和反应波形特点,P1、N1及N2波形态、振幅密度及潜伏期。结果CRT及LED刺激器mfERG一阶反应波形基本相似；CRT及LED刺激器的mfERG二阶反应波形不同,前者的P1波呈尖峰状,后者的P1波较宽,呈方形,且伴有一个较深的N2波。随着刺激时间的延长,LED刺激器的mfERG一阶及二阶反应中的P1波及N1波的振幅密度增加,潜伏期延长。结论CRT及LED刺激器的mfERG一阶反应波形基本相同,但LED的二阶反应波形更丰富,其可能包涵了更多视网膜内层信息。(眼科,2006,15：351-355)
Objective To investigate the waveform of the first-order kernel and second-order kernel of multifocal electroretinogram stimulated with light emitting diode （LED）. Design Prospective, noncomparative, interventional case series. Participant 18 subjects（18 eyes） who had been accepted the mfERG test. Method The patients were devided into two groups, they accepted the multifocal electroretinogram（mfERG） stimulated with cathode ray tube （CRT） and LED using the Roland RETI Scan3.15 system. The first-order kernel or the second-order kernel was analyzed. The stimulation time of LED were changed from 1.7ms to 16.7ms. Five different stimulation time of LED in this study were 1/10（1.7ms）, 3/10（Sins）, 5/10（8.3ms）, 7/10（11.7ms） and 10/10（16.7ms）. Main Outcome Measure The summed responses were observed. The waveform, amplitude and implicit times of mfERG summed response were analyzed. Result The waveforms of the first-order kernel stimulated by LED were similar to those of CRT. In the second-order kernels of mfERG, the waveforms were obviously different from those stimulated by LED and CRT. The P1 wave stimulated by CRT was sharp, but the P1 wave of LED was broad. The N2 wave of LED was deeper. The amplitude of N1 wave and P1 wave were increased, and their implicit times prolonged with the stimulation times prolonging. Conclusion In the first-order kernel of mfERG, the waveform of the summed response stimulated by LED was similar to that of LED. In the second-order kernel of mfERG, the waveform stimulated by LED was morecom plicated, may be there were more inner retina information.
出处
《眼科》
CAS
2006年第5期351-355,共5页
Ophthalmology in China
