摘要
以肌苷为原料,通过乙酰化、氯化、氨解得到腺苷,总收率≥50%。
A new synthetic method of adenosine from inosine was reported. Firstly, inosine reacted with acetic anhydride to produce 2＇, 3＇, 5＇-Triacetylinosine ; 2＇, 3＇, 5＇-Triacetylinosine reacted with Vilsmeier reagent to produce 6-chloro-2＇, 3＇, 5＇-Triacetyl-9-β-D- ribo furanosyl-purine, then the product was treated with NH3- CH3OH to produced adenosine.The total yield was up to 50%.
出处
《化学试剂》
CAS
CSCD
北大核心
2006年第10期633-634,共2页
Chemical Reagents
关键词
腺苷
肌苷
adenosine
inosine
