摘要
目的探讨如何提高肝移植手术成功率,减少并发症及提高患者生存率。方法就我院2002年10月 ̄2006年3月行尸肝原位肝移植病人28例:其中原发性肝癌14例,急性重症肝炎2例,亚急性重症肝炎3例,乙肝肝硬化8例,胆汁性肝硬化1例,术后全程随访,随访时间4 ̄45个月,观察病人术后并发症及生存时间。结果围手术期死亡1例,手术成功率96.43%(27/28);术后死亡4例,其余均生存至今。1、2、3年生存率分别为89%、86%与82%。术后发生各种并发症7例,包括:胸腔内出血、呼吸道感染、单纯性疱疹、霉菌性肠炎、呼吸心跳骤停复苏后持续植物状态、轻微胆漏、黄疸。并发症发生率25%。结论肝移植已成为各类不可逆性终末期肝病的根本治疗方法,经典原位肝移植仍是一种较成熟的、可靠的手术方式,坚持使用术者熟悉的手术方式,及术中谨慎操作有利于减少各种并发症的发生。
Objective To discuss how to achieve high anccessful rate of hver transplantation and to increase the survival with less complications,Methods Twenty eight cases of orthotopic liver transplantation perfomed in our center from Oct/2002 to Mar/2006 were analysed .All the cases include: primary hepatic carcinoma 14 caes, acute serious hepatitis 2 cases ,subacute hepatitis 3 cases, hepatitis B virus cirrhosis 8 cases , biliary cirrhosis 1 case. The modus operandi was noncartliopalmus donor classic orthotopic hver transplantation . And all the cases were followed up in whole period (from 4 months to 44 months ). Results The operation achievement rate was 96%(27/28); Only 1 patient died during the operation, 4 died after thee operation ; others had were still living up to now. 1,2,3 year survival was 89% ,86% ,82%respectively . The complication incidence was 25% , which was happened in 7 patients, including thoracic cavity entorrhagia ,respiratory" inffecfion, herpes catarrhalis , mould enteritis, light bile leakage, jaundice, diabetes and vegetative state after cardiopulmonary resuscitation . Conclusion Liver transplantation has become an essential treatment method for irreversible liver diseases in terminal stage hepatopathy. The elasaic orthotopic liver transplantation is still a good modus. A familiar operation typer for the performer with cautious operation is less compications.
出处
《江西医药》
CAS
2006年第9期625-627,共3页
Jiangxi Medical Journal
关键词
经典原位肝移植
病例报告
classic orthotopic liver transplantation
case report