摘要
为探讨剖宫产术中母体、胎盘肾素-血管紧张素Ⅱ-醛固酮系统(RAAS)的变化及麻醉效果对RAAS的影响,用RIA法测定30名行择期剖宫产的健康产妇血浆肾素活性(PRA)、血管紧张素Ⅱ(ATⅡ)和醛固酮(ALD)浓度。结果表明,注射麻醉药前(T0)与术毕即刻(T1)相比较,产妇静脉血PRA、ATⅡ值有明显差异(分别P<0.01,P<0.05),ALD值差异无显著性。脐动脉血、脐静脉血、胎盘血中上述指标无显著性差异。麻醉平稳、阻滞效果良好者与麻醉效果欠佳、阻滞不全者相比,PRA、ATⅡ和ALD值均有明显差异。RAAS参与了分娩前后的生理过程,剖宫产手术围术期间应采取稳定RAAS的措施,维持麻醉、手术中母婴安全。
To study changes of renin-angiotensin-aldosterone system （RAAS） and influence of anesthetic effect on it during caesarean operation, PRA, AT Ⅱ and ALD in maternal and placental blood were determined by RIA for 30 healthy women scheduled for caesarean operation. Blood was taken before anesthesia（T0 group） and just at the end of surgery （T1 group） for comparison. Results showed that there were significant differences in PRA（P〈0.01） and AT Ⅱ （P 〈0.05） in vein blood between To and T1 group, but there were no significant differences in ALD, PRA and AT Ⅱ between placental blood, umbilical arteria and vein blood. The data suggest that there was obvious relationship between anesthetic effect and the secretion of RAAS. The levels of AT Ⅱ , ALD and PRA in patients of partial block anesthesia were significantly higher than those in patients of complete block anesthesia.
出处
《标记免疫分析与临床》
CAS
2006年第3期147-149,共3页
Labeled Immunoassays and Clinical Medicine
关键词
剖宫产
肾素
血管紧张素Ⅱ
醛固酮
Caesarean operation
Rennin
Angiotensin Ⅱ
Aldostercme
