摘要
用光镜和电镜观察乙状结肠直肠全层脱垂肠段肠壁内神经丛神经元的形态结构改变。结果表明,脱垂肠管的肌间神经丛和粘膜下神经丛的神经细胞发生尼氏体溶解或浓缩呈团块状,细胞核偏位和浓缩变小,细胞肿大或萎缩,神经节内细胞减少,胶质细胞增生;电镜下可见神经细胞粗面内质网肿胀、脱颗粒,线粒体肿大、嵴消失或呈空泡,高尔基复合体扩张等超微结构的改变。认为肠管直肠脱垂时肠壁内神经丛的损害在此病发生发展过程中,可能起着重要作用。
The alternation of enteric nervous plexus with prolapse of all layers of the sigmoid colon and rectum was observed under the lightmicroscope and electromicroscope. The dissolution and contraction of Nissl′s bodies, swelling or shiriveling of the nucleus and incrassation of nucleus were seen in the ganglionic cells in the intermuscular plexus and submucosal plexus. The number of ganglionic cells reduced and the number of glial cells increased. Swelling of rough endoreticulation and the mitochondria was not empty.
出处
《中国医科大学学报》
CAS
CSCD
1996年第6期639-640,共2页
Journal of China Medical University