摘要
目的探讨干扰素联合山莨菪碱及叶酸治疗轮状病毒性肠炎的临床疗效。方法将80例患儿随机分为两组:治疗组加用干扰素、山莨菪碱及叶酸(n=40例)、对照组加用病毒唑(n=40例);并分别评估治疗效果。结果治疗组显效率37.5%,有效率55%,无效率7.5%;病毒唑组显效率20%,有效率50%,无效率30%。两组率的比较x2=7.63,P<0.05。结论对于婴幼儿秋冬季腹泻,干扰素联合山莨菪碱及叶酸早期应用于轮状病毒肠炎比单用利巴韦林抗病毒治疗效果好,临床值得采用。
Objective To evaluate the clinical therapeutic efficacy of recombinant α-Ib interferon anisodaminc and folic acid in treating infantile diarrhea infected with rotavirus. Methods 80 cases were randomly divided into two groups： recombinant α-Ib interferon, anisedaminc and folic acid treatment group （n=40）, ribavirin treatment group （n=40）, clinical results were evaluated aftcrtreatmcnt. Results In recombinant α-Ib interferon, anisodmine and folic acid treatment group, the cure rate were 37.5%, the effective rate were 55%, the inefficient rate were 7.5%. In ribavirin treatment group, the cure rate were 20%, the effective rate were 50%, the inefficient rate were 30%, Compare these date, x^2=7.63, p〈0.05. Conclusions In treating with infantile diarrhea infected with rotavirus, recombinant α-Ib interferon, anisodaminc and folic acid are better than ribavirin.
出处
《海南医学》
CAS
2006年第11期1-1,3,共2页
Hainan Medical Journal
关键词
干扰素
山莨菪碱
叶酸
病毒唑
婴幼儿腹泻
轮状病毒
Recombinant α-Ib interferon Anisodamine Folie acid Ribavirin
Infantile diarrhea
Rota Virus
