摘要
目的:了解慢性心房纤颤(房颤)并发脑梗死患者的凝血、纤溶功能状态。方法:所有受试对象均在入院时抽取静脉血送检凝血、纤溶功能指标。结果:慢性房颤并发脑梗死患者的Fb、D-dimer及VWF:Ag明显增高,与单纯房颤组(对照组)对比,经统计学处理具有显著意义(P<0.05);而APTT、PT虽短于对照组,但经比较无统计学意义。结论:慢性房颤并发脑梗死患者发病时Fb、D-dimer及VWF:Ag明显增高,反映了这些患者存在凝血、纤溶功能的紊乱,同时也间接预示凝血、纤溶指标增高的慢性房颤患者有可能出现脑梗死。
Objective： To study the changes of clotting and fibrinolysis in patients with chronic atrial fibrillation complicated by cerebral infarction. Methods： Tests of PT、APTT、VWF：Ag、D-dimer and Fb were detected in these patients and the control group （the patients with simple atrial fibrillation） at admission. Results： The results of VWF：Ag 、D-dimer and Fb were higher in the patients with chronic atrial fibrillation complicated by cerebral infarction than in the control group at admission, there was a significant difference between two groups（P 〈 0.05）. APTT and PT were shorter than the control group, there were no statistic significance between two groups （P 〉 0.05）. Conclusions： The results suggested that the patients with chronic atrial fibrillation complicated by cerebral infarction had clotting and fibrinolysia turbulence. Whereas the increase of plasma VWF：Ag,D-dimer and Fb in the patients with chronic atrial fibrillation indirectly indicated that they would been complicated by cerebral infarction.
出处
《岭南急诊医学杂志》
2006年第5期339-340,共2页
Lingnan Journal of Emergency Medicine
关键词
慢性房颤
纤溶
凝血
脑梗塞
chronic atrial fibrillation
fibrinolysis
clotting
cerebral infarction
