期刊文献+

改良性电抽搐治疗难治性抑郁症的效果 被引量:2

下载PDF
导出
摘要 目的探讨合并改良性电抽搐治疗(modified electrocomvulsive therapy,MECT)难治性抑郁症的临床疗效及安全性。方法65例难治性抑郁症患者随机分为两组,MECT组(33例)在原用抗抑郁剂的基础上加用MECT治疗。对照组(32例)使用原有抗抑郁剂。所有入组患者完成汉密尔顿抑郁量表(HAMD)、大体评定量表(GAS)、副反应量表(TESS)评定。总疗程4周。结果MECT组在治疗4周后HAMD总分值明显下降,对照下降不明显,MECT组显效率为60.6%,明显高于对照组的25.0%(P<0.01)。两组TESS分值无差异。结论加用MECT治疗难治性抑郁症是安全、有效的。
出处 《广东医学》 CAS CSCD 北大核心 2006年第10期1521-1523,共3页 Guangdong Medical Journal
  • 相关文献

参考文献6

二级参考文献18

  • 1[1]Sackeim HA. The definition and meaning of treatment resistant depression. J Clin Psychiatry, 2001,62 [Suppl,16]:10~17 被引量:1
  • 2[2]Nierenberg AA, DeCecco LM. Definitions of antidepressant treatment response, remission, non-response, partial response, and other relerant outcomes:a focus on treatment-resistant depression. J Clin Psychiatry, 2001, 62[Suppl, 16]: 5~9 被引量:1
  • 3[3]Kornstein SG, Schneider RK, Clinical features of treatment depression. J Clin Psychiatry, 2001,62[Suppl, 16] :18~25 被引量:1
  • 4[4]Frazer A. Norepinephrine involvement in antidepressant action. J Clin Psychiatry, 2000,61 [Suppl, 10]: 25 ~ 30 被引量:1
  • 5[5]Gorman JM,Sullivan G. Noradrenergic approaches to antidepressant therapy. J Clin Psychiatry, 2000,61 [Suppl,1]:13~16 被引量:1
  • 6[6]Fava M. Augmentation and combination strategies in treatment-resistant depressant . J Clin Psychiatry, 2001,62[Suppl,18] :4~11 被引量:1
  • 7[1]Sackeim HA. The definition and meaning of treatment-resistant depression. J Clin Psychiatry, 2001, 62 (Suppl 16) : 10 ~ 17 被引量:1
  • 8[2]Posternak MA, Zimmnenman M. Switcting versus augmentation: a prospective, naturalistic comparison in depressed, treatment-resistant patients. J Clin Psychiatry, 2001, 62(2) : 135 ~142 被引量:1
  • 9[3]Killer MB, Pinder RM. The rode of mirtazapine in pharmacotherapy of depression. J Clin Psychiatry, 2000, 61 : 609 ~616 被引量:1
  • 10[4]Anttila SA, Leinonen EV. A review of the pharmacological and clinical profile of mirtazapine. CNS Drug Reviews, 2001, 7 : 249 ~264 被引量:1

共引文献30

同被引文献33

  • 1李喆,孙学礼,黄颐,张波.难治性抑郁症患者认知功能特点及其与神经内分泌的相关性研究[J].中国循证医学杂志,2007,7(8):575-579. 被引量:34
  • 2NEMEROFF C B. Prevalence and management of treatment - resistant depression[J]. J Clin Psychiatry, 2007, 68(Suppl 8) : 17 -25. 被引量:1
  • 3LO0 C K, KAILL A, PATON P, et al. The difficult - to - treat electroconvulsive therapy patient - Strategies for augmenting out-comes[J]. JAffect Disord, 2010, 124(3): 219-227. 被引量:1
  • 4HUSAIN M M, RUSH A J, FINK M, et al. Speed of response and remission in major depressive disorder with acute electroconvulsive therapy (ECT) : a Consortium for Research in ECT (CORE) re- port[J]. J Clin Psychiatry, 2004, 65(4) : 485 -491. 被引量:1
  • 5AUTRY A E, ADACHI M, NOSYREVA E, et al. NMDA recep- tor blockade at rest triggers rapid behavioural antidepressant re- sponses[J]. Nature, 2011,475(7354): 91 -95. 被引量:1
  • 6LOO C B, SIMPSON B, MACPHERSON R. Augmentation strategies in electroconvulsive therapy[J]. J ECT, 2010, 26(3) : 202 -207. 被引量:1
  • 7ZARATE C A Jr, MATHEWS D, IBRAHIM L, et al. A random- ized trial of an N - methyl - D - aspartate antagonist in treatment - resistant major depression [ J]. Arch Gen Psychiatry, 2006, 63 (8) : 856 - 864. 被引量:1
  • 8OKAMOTO N, NAKAI T, SAKAMOTO K, et al. Rapid antide- pressant effect of ketamine anesthesia during electroconvulsivc ther- apy of treatment - resistant depression: comparing ketamine and propofol anesthesia[ J ]. J ECT, 2010, 26 (3) : 223 - 227. 被引量:1
  • 9DIAZGRANADOS N, IBRAHIM L, BRUTSCHE N E, et al. A randomized add - on trial of an N - methyl - D - aspartate antago- nist in treatment -resistant bipolar depression[ J]. Arch Gen Psy- chiatry, 2010, 67(8): 793 -802. 被引量:1
  • 10PRICE R B, NOCK M K, CHARNEY D S, et al. Effects of intra- venous ketamine on explicit and implicit measures of suicidality in treatment - resistant depression [ J ]. Biol Psychiatry, 2009, 66 (5) : 522 -526. 被引量:1

引证文献2

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部