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内外科综合治疗感染性心内膜炎 被引量:2

Infective Endocarditis Comprehensively Treated with Internal Medicine and Surgery
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摘要 目的 探讨内、外科综合治疗感染性心内膜炎的价值。方法 对62例感染性心内膜炎,术前使用大剂量青霉素与庆大霉素,其中15例行急诊手术,16例行亚急诊手术,31例行择期手术。手术主要清理赘生物、被感染的瓣膜组织及瓣周脓肿,并矫治心内病变。结果 无手术死亡。术后死亡4例,58例治愈出院。除3例失访外,其余随访2年心功能均恢复到Ⅰ-Ⅱ级。结论 在抗感染同时积极采取外科干预治疗能有效降低感染性心内膜炎的病死率。 Objective To discuss the significance of comprehensive treatment with internal medicine and surgery for infective endocarditis. Methods A total of 62 patients with infective endocarditis were administered the large dose of penicillin and gentamicin before surgical operation. Of the patients, 15 were performed with emergency operation, 16 with sub-emergency operation, and 31 with elective surgery. The surgical operation consisted mainly of the clearance of vegetation and infected valvular tissue, and the repair of intracardiac lesion. Results None died during the operation. Four patients died after operation, and the other 58 ones left the hopital when healed up. According to the two years" follow-up, an improvement in cardiac function to grade Ⅰ or Ⅱ was achieved in all the 58 patients except the three ones who lost follow-up. Conclusion The case - fatality rate of infective endocarditie can be effectively lowered as soon as active surgical intervention is employed in addition to anti-infection.
机构地区 解放军第
出处 《临床军医杂志》 CAS 2006年第5期557-558,共2页 Clinical Journal of Medical Officers
关键词 感染性心内膜炎 抗生素疗法 手术治疗 infective endocarditis antibiotic therapy surgical operation
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  • 1周令仪.感染性心内膜炎[M]//.彭文伟.感染性疾病与传染病学,北京:科学出版社,2000:1862-1890. 被引量:3
  • 2Sachdev M,Peterson C E,Jolis J G.Imaging techniques for diagnosis of infective endocarditis[J].Cardiol Clin,2003,21 (2):185-195. 被引量:1
  • 3Olaison L,Pettersson G.Current best practices and guidelines.Indications for surgical intervention in infective endocarditis[J].Cardiol Clin,2003,21 (2):235 -251. 被引量:1
  • 4Alexiou C,Langley S M,Stafford H,et al.Surgical treatment of infective mitral valve endocarditis:predictors of early and late outcome[J].J H eart Valve Dis,2000,9(3):327 -334. 被引量:1
  • 5Delabaye F,Celard M,Roth O,et al.Indication and optimal timing for surgery in infective endocarditis[J].Heart,2004,90:618-620. 被引量:1

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