摘要
目的探讨初治失败及复发肺结核病人的复治化疗效果。方法对96例初治失败及复发肺结核病人采用两种不同的复治方案化疗,实验组(48例)化疗方案为2DZEThAk(Lv)/1DZETh/5DETh;对照组(48例)化疗方案为2H3R3Z3E3S3/6H3R3E3,均实施强化期督导管理。结果实验组治愈42例,复治失败2例;对照组治愈32例,复治失败10例,实验组治愈率优于对照组(2χ=5.90,P<0.05,失败率低于对照组(χ2=6.10,P<0.05。结论初治失败及复发肺结核患者,可能存在较高的初始和继发耐药。建议这类患者常规进行结核菌培养及药敏试验,有针对性地合理实施复治化疗,提高治愈率,降低病死率及复治失败与复发率。
Objective To explore clinical effect on first-time treatment-failed and recurred tuberculosis patients, Methods A total of 96 first-time treatment-failed and recurred tuberculosis patients were divided into two groups： the experiment group （n = 48 ） was given 2DZEThAk （ Lv）/1DETh and the control group （n =48） were given 2H3R3Z3E3S3/6H3R3E3. Results In the experimental group, 42 cases were cured and 2 failed. In the control group, 32 were cured and 10 failed. The cure rate in the experimental group was better than the control （ P 〈0. 05 ） and the failure rate in the experimental group was lower than that in the controls （ P 〈0. 05 ）. Conclusion The first-time treatment-failed and recurred tuberculosis patients should be given regular tuberculosis bacteria examination and regular drug - resistance checkup to improve cure rate and lower mortality and failure rate.
出处
《临床肺科杂志》
2006年第6期741-742,共2页
Journal of Clinical Pulmonary Medicine
