摘要
制备了注射用载胸苷激酶(TK)基因质粒PLGA纳米粒的冻干剂,并对其形态、粒径、稳定性、体外抗核酸酶和抗超声能力等进行了观察。结果表明,纳米粒可提高TK基因对核酸酶和超声的抵抗能力。
The injectable lyophilized nanoparticles loaded with thymine kinase gene was prepared.The morphology,particle,preliminary stability,anti-nuclease ability and anti-ultrasonic radiation of the products were investigated.The results showed that the nanoparticles could enhance the resistance ability of plasmid DNA to nuclease or ultrasound.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2006年第10期682-684,共3页
Chinese Journal of Pharmaceuticals
