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胰岛B细胞脂性凋亡研究进展 被引量:5

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出处 《中国实用内科杂志》 CAS CSCD 北大核心 2006年第10期1553-1555,共3页 Chinese Journal of Practical Internal Medicine
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参考文献16

  • 1Girard J.Contribution of free fatty acids to impairment of insulin secretion and action mechanism of beta-cell lipotoxicity[J].Med Sci (Paris),2005,21:19 -25. 被引量:1
  • 2卜石,杨文英,王昕,潘琳.脂毒性对大鼠胰岛细胞凋亡的作用[J].中华糖尿病杂志(1006-6187),2004,12(6):433-436. 被引量:32
  • 3Piro S,Anello M,Di Pietro C,et al.Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets:possible role of oxidative stress[J].Metabolism,2002,51 (10):1340 -1347. 被引量:1
  • 4Maedler K,Oberholzer J,Bucher P,et al.Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta -cell turnover and function[J].Diabetes,2003,52 (3):726-733. 被引量:1
  • 5Lupi R,Dotta F,Marselli L,et al.Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets:evidence that beta-cell death is caspase mediated,partially dependent on ceramide pathway,and Bcl -2 regulated[J].Diabetes,2002,51 (5):1437-1442. 被引量:1
  • 6Fariss MW,Chan CB,Pat EL,et al.Role of mitochondria in toxic oxidative stress[J].Mol Interv,2005,5:94-111. 被引量:1
  • 7Lingohr MK,Dickson LM,Wrede CE,et al.Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis,which can be compensated for by introduction of IRS-4 expression[J].Mol Cell Endocrinol,2003,209 (1-2):17-31. 被引量:1
  • 8Wrede CE,Dickson LM,Lingohr MK,et al.Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta -cells (INS-1)[J].J Biol Chem,2002,277 (51):49676 -49684. 被引量:1
  • 9Lin CY,Gurlo T,Haataja L,et al.Activation of peroxisome proliferator-activated receptor -gamma by rosiglitazone protects human islet cells against human islet amyloid polypeptide toxicity by a phosphatidylinositol 3-kinase-dependent pathway[J].J Clin Endocrinol Metab,2005,90 (12):6678-6686. 被引量:1
  • 10Lalloyer F,Vandewalle B,Pereevault F,et al.Peroxisome proliferator-activated receptor { alpha } improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets[J].Diabetes,2006,55 (6):1605 -1613. 被引量:1

二级参考文献5

  • 1Pick A,Clark J, Kubstrup C, et al. Role of apoptosis in failure of β cell mass compensation for insulin resistance and B cell defects in the male Zucker diabetic fatty rat. Diabetes, 1998,47:358-364. 被引量:1
  • 2Butler AE, Janson J, Bonner-Weir S, et al. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2diabetes. Diabetes, 2003,52:102-110. 被引量:2
  • 3Maedler K, Oberholzer J, Bucher P, et al. Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. Diabetes,2003,52:726-733. 被引量:2
  • 4Shimabukuro M, Zhou YT, Levi M, et al. Fatty acids induced B cell apoptosis:a link between obesity and diabetes. Proc Natl Acad Sci USA,1998,95:2498-2502. 被引量:1
  • 5Shimabukuro M, Wang MY, Zhou YT, et al. Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression. Proc Natl Acad Sci U S A, 1998,95:9558-9561. 被引量:1

共引文献31

同被引文献49

引证文献5

二级引证文献31

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