摘要
目的探讨深静脉导管送检标本的病原学特征及细茵耐药性。方法回顾分析2001-08～2006-05期间送检的3189例次深静脉导管标本的病原学结果及细菌耐药性。结果3189份标本中,病原学阳性471份(14．77%),共检出病原茵514株,G^+菌、G^-菌和真菌分别占42．41%、40．66%和16．93%。五种最常见的病原茵分别为表皮葡萄球菌(15．56%)、金黄色葡萄球菌(13．81%)、铜绿假单胞菌(13．23%)、肺炎克雷伯菌(7．59%)和鲍曼不动杆菌(6．23%)；金黄色葡萄球茵中MRSA占91．18%,凝固酶阴性葡萄球茵中MRScn占88．57%,肠杆菌科中产ESBLs占12%；铜绿假单胞菌和鲍曼不动杆菌的耐药率呈上升趋势,并出现了全耐药菌株。结论深静脉导管标本检出的病原菌以耐药茵为主,加强病原学监测以及导管护理,避免交叉感染,是控制深静脉导管相关感染发生的关键。
Objective To investigate the characteristics of the organisms of deep - venous catheter （ DVC） tip culture and their antibiotics resistance. Methods The culture results of 3189 DVC tip were analyzed retrospectively from August 2001 to May 2006. Results Among 3189 catheter tip cultures, 471 （ 14.77% ） were positive with 514 microorganisms ： G^＋ bacteria accounted for 42.41%, G- bacteria 40. 66%, and yeasts 16. 93%. The five most common microorganisms were Staphylococcus epidermidis （15.56% ）, Staphylococcus aureus（ 13.81% ）, Pseudomonas aeruginosa（ 13.23% ）, Klebsiella pneumoniae（ 7.59% ） and Acinetobacter baumanii （6.23% ） respectively. 91.18% of Staphylococcus aureus were MRSA, 88.57% of Staphylococcus epidermidis were MRScn and 12% of Enterobacter were ESBLs. The Pseudomonas areuginosa and Acinetobacter baumanii had an increasing tendency in drug - resistance rate and some of them were multiple drug - resistant. Conclusion The most common pathogens cultured from the DVC were drug - resistant. It＇ s key to enforce the etiological monitor and the medical attendance of catheters and to prevent cross infection for controlling the catheter- related infection.
出处
《中国急救医学》
CAS
CSCD
北大核心
2006年第10期652-655,共4页
Chinese Journal of Critical Care Medicine
关键词
深静脉导管
病原学
耐药性
Deep - venous catheter
Etiology
Drug resistance
