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洛伐他汀对正常血脂稳定型心绞痛患者预后的影响

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摘要 目的探讨他汀类药物对血脂正常的稳定型心绞痛患者预后的影响。方法对92例确诊稳定型心绞痛的患者,随机分为治疗组(洛伐他汀组)50例和对照组42例,两组均给予常规抗血小板、抗心肌缺血治疗,治疗组在此基础上加服洛伐他汀胶囊20 mg,睡前服用,经过12个月治疗,分析比较两组心脏缺血相关事件。结果两组治疗前和治疗3个月时心肌缺血总负荷(TIB)相比无显著性差异(P<0.01),治疗组1年时总缺血相关事件的发生率低于对照组(P<0.05)。结论血脂正常的稳定型心绞痛患者服用洛伐他汀后减少缺血相关事件发生,冠心病患者从中受益不仅来自于其降脂作用,而且来自于该药在稳定斑块,改善炎症,降低血小板聚集等方面的非降脂作用。
作者 彭军 何国欢
出处 《右江医学》 2006年第5期476-477,共2页 Chinese Youjiang Medical Journal
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