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桃红四物汤加味治疗复发性口疮临床研究及其与血瘀症的关系 被引量:5

Clinical observation of recurrent aphthous ulcers and the relation of blood stasis syndrome treated by Taohong Siwu decoction
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摘要 目的通过与P-转移因子口服液的临床疗效比较,评价桃红四物汤加味对复发性口疮(RAU)的治疗效果。方法将确诊为RAU的60例患者按1∶1的比例随机分成两组:桃红四物汤加味组、P-转移因子口服液组。分别口服6d后,观察各组主观症状和症候的改善情况,评价其治疗效果。结果桃红四物汤加味能显著改善局部微循环,对血液流变学的各项指标及各项临床症状和体征均有明显改善作用,桃红四物汤加味治疗的30例RAU中,痊愈3例,显效21例,有效5例,无效1例,总有效率为96.7%,治疗效果显著性优于对照药P-转移因子口服液(P<0.05)。结论桃红四物汤加味具有良好的活血化瘀、清热解毒的作用,能明显改善局部微循环和免疫功能,其临床疗效明显好于P-转移因子口服液。 Objective To estimate the therapeutic effects of Taohong Siwu decoction(TSD) on recurrent aphthous ulcer (RAU). Methods Sixty cases with recurrent aphthous ulcer were randomly divided into the TSD group and the P-aversion factor(P-AF) group, with 30 in each. The TSD group were treated with TSD and those in P-AF group were treated with P-AF. All lasted for six days. Results The function of TSD could significantly improve partis microcireulation in recurrent aphthous ulcer, and could significantly improve clinical symptoms and each index of hemorheology. The effective rate of TSD was 96.7% for recurrent aphthous ulcer. The therapeutic efficacy of TSD are much better than the P-AF(P〈0.05). Conclusion The TSD has effects of heat-clearing,and detoxicating and removing blood stasis, and can significantly improve the partis microcireulation and the immunology function. The TSD has better effect than the P-AF.
出处 《中国药物与临床》 CAS 2006年第9期667-669,共3页 Chinese Remedies & Clinics
基金 湖南省教育厅基金资助项目(03C286)
关键词 桃红四物汤 口腔溃疡 生物医学研究 P-转移因子口服液 Taohong Siwu decoction, Oral ulcer , Biomedical research P-aversion factor
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  • 1吴少鹏 谢勋 等.女性复发性口疮微循环血液流变学研究[J].口腔医学,1995,5(4):169-171. 被引量:1
  • 2李秉琦.实用口腔黏膜病学(第1版)[M].成都:四川科学技术出版社,1987.102-109. 被引量:1

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