摘要
目的研究水通道蛋白-1在培养的牛角膜内皮细胞中的表达情况及意义。方法用免疫组织化学方法,检测水通道蛋白-1在培养的牛角膜内皮细胞中的表达。结果培养的牛角膜内皮细胞中有水通道蛋白-1的表达,且主要位于细胞膜上。结论牛角膜内皮细胞中的水通道蛋白-1在角膜内皮液体转运中起着重要作用,其表达改变可能导致角膜水肿和功能改变。
Objective To investigate the expression of aquaporins-1 ( AQP-1 ) in cultured bovine corneal endothelial cells (CBCEC) . Methods Immunohistoehemisty was used to detecting AQP-1 expression in CBCEC. Results The presence of AQP-1 antibody was major located in CBCEC membrane. Conclusion AQP-1 in CBCEC play an important role in corneal endothelial cell' s fluid transport, its expression change may cause corneal edema and function disorder.
出处
《临床眼科杂志》
2006年第5期466-467,共2页
Journal of Clinical Ophthalmology