摘要
探讨子宫肌瘤行经导管子宫动脉栓塞(TUAE)治疗后的病理变化及临床意义。研究证实,TUAE后肌瘤组织随时间改变呈现动态病理变化,即先发生充血、水肿,随后发生坏死,最后出现纤维组织增生,这一动态病理变化是TUAE后肌瘤体积不断缩小的病理基础。绝大多数肌瘤呈不完全坏死,因此肌瘤可能复发。影响坏死范围的因素包括肌瘤大小与部位及栓塞后时间长短。TUAE后正常子宫组织可能出现炎症反应,但无坏死改变。周围附件器官末梢血管发现栓塞剂,提示TUAE对卵巢、输卵管功能有潜在的影响。
Pathological changes of uterine fibroide after transcatheter uterine artery embolization （TUAE） has been proven with regular pathological change during the elapse time after TUAE resulting in fibrotic proliferation. Inflammation took place first, followed by coagulation necrosis and hyaline degeneration but incomplete in most cases and finally with proliferative fibrous tissue formation. These dynamic changes of pathology are basis for fibroid volume reduction and recurrences. The factors affecting the extent of fibroid necrosis included tumor size,position and elapse of duration after TUAE. Inflammation was found in normal uterine tissue after TUAE but no necrosis occurred. The finding of embolization agent in peripheral vessels of adnexa may suggest future possible damage of function in ovary and fallopian tube. （J Intervent Radiol, 2006, 15： 507-509）
出处
《介入放射学杂志》
CSCD
2006年第8期507-509,共3页
Journal of Interventional Radiology
基金
广东省卫生厅高难
高新技术项目(C2000031)
广东省医学科研课题(A2001065)
关键词
子宫肌瘤
栓塞
治疗性
病理学
Uterine fibroid
Embolization, therapeutic
Pathology
