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肺癌中腺癌与鳞癌肿瘤细胞P-糖蛋白的表达差异 被引量:1

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摘要 目的研究肺癌患者中腺癌与鳞癌肿瘤细胞多药耐药性(multidrugresistant,MDR)的表达。方法应用流式细胞仪检测35例患者肿瘤细胞P-糖蛋白(P-glycoprotein,P-gp)的表达。结果35例患者中20例腺癌患者的P-gp阳性率明显高于15例鳞癌患者,差异有显著性(P<0.05)。结论P-gap高表达可能是非小细胞肺癌产生内在耐药性的机制之一。
出处 《临床输血与检验》 CAS 2006年第3期204-205,共2页 Journal of Clinical Transfusion and Laboratory Medicine
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