摘要
目的：采用多巴酚丁胺负荷超声心动图评价急性心肌梗死后梗死区域心肌的存活性。方法：３６例急性心肌梗死病人进入本研究，分别采用５μｇｋｇ－１／ｍｉｎ和１０μｇｋｇ－１／ｍｉｎ的多巴酚丁胺静脉滴注，体表超声心动图观察梗死区域心肌收缩心室壁运动和厚度的变化，以识别有无存活心肌。结果：对３６例病人分析了５７６段心肌，基础状态时９４段心肌运动消失；１１９段心肌运动减低；３６３段心肌为正常心肌。静脉滴注５μｇｋｇ－１／ｍｉｎ多巴酚丁胺后，运动消失的９４段心肌中，３０段心肌心室壁运动及收缩心室壁增厚率得到了改善，其中２３段心肌变为运动减弱心肌，７段心肌变为正常心肌，将多巴酚丁胺增量至１０μｇｋｇ－１／ｍｉｎ后，由第１次剂量无反应的运动消失的６４段心肌中，有５段心肌心室壁运动和收缩心室壁增厚率得到改善。结论：采用多巴酚丁胺负荷超声心动图对急性心肌梗死后存活心肌的识别是安全的，而且具有十分重要的临床意义。
Objective:To observe myocardial viability of infarcted area in patients with acute myocardial infarction(AMI) by echocardiography during infusion of dobutamine. Methods:We studied 36 selected patients with AMI.The effect of dobutamine infusion (5 μg/kg body weight per min and 10 μg/kg per min) on left ventricular systolic wall motion and thickening was evaluated by transthoracic echocardiography in order to identity myocardial viability. Results:Ninety four from 576 Myocardial segments were akinetic,and their rates of increasing thickness of ventrcular wall in systole were all zero at baseline.After dobutamine infusion (5 μg/kg·min)35/94 (37 2%) segments regained viability and became normokinetic or hypokinetic. Conclusion:Echocardiography during infusion of low dose dobutamine is a safe and reliable method which is of certain clinical significance for identifying myocardial viability after AMI.
出处
《中国循环杂志》
CSCD
1996年第11期645-647,共3页
Chinese Circulation Journal
关键词
多巴酚丁胺
超声心动图
存活心肌
急性
心肌梗塞
Dobutamine
Stress echocardiography
Myocardial viability
Acute myocardial infarction (Chinese Circulation Journal,1996,11:645.)
