摘要
Objective: Validate Digital Cervicography as adjunctive cervical cancer screening test to VIA and Cytology. Method: Women (1292) were submitted to both cytological and VIA tests to obtain a sample of 301 positive VIA cases (23.3% ) which have had the Digital Cervicography (DC) taken and evaluated. Just cases considered positive by DC (149/301 cases- 49.5% )- and/or positive Pap smear tests were referred to colposcopy and biopsy whenever indicated. Results: Cervical smear was positive in 5.4% , including LGSIL (4% ), HGSIL (1% ) and one case of invasive cancer (0.4% ), and 1.6% of ASCUS or AGUS.DC identified 81 positive cases (74 LGSIL; 5 HGSIL; 2 cancers). The sensitivity of cytology was 14.8% , and the DC was 100% . Corresponding specificities were 95.4% and 69.1% , respectively. The NPV and PPV for DC were 100% and 54.4% . Conclusion: DC increases sensitivity, specificity and positive predictive value of VIA, becoming a valid adjunctive screening test for cervical cancer in low resource settings.
Objective： Validate Digital Cervicography as adjunctive cervical cancer screening test to VIA and Cytology. Method： Women （1292） were submitted to both cytological and VIA tests to obtain a sample of 301 positive VIA cases （23.3%） which have had the Digital Cervicography （DC） taken and evaluated. Just cases considered positive by DC （ 149/301 cases - 49.5% ） - and/or positive Pap smear tests were referred to colposcopy and biopsy whenever indicated. Results： Cervical smear was positive in 5.4%, including LGSIL （4%）, HGSIL （1%） and one case of invasive cancer （0. 4% ）, and 1.6% of ASCUS or AGUS. DC identified 81 positive cases （74 LGSIL; 5 HGSIL; 2 cancers）. The sensitivity of cytology was 14. 8%, and the DC was 100%. Corresponding specificities were 95.4% and 69.1%, respectively. The NPV and PPV for DC were 100% and 54.4%. Conclusion： DC increases sensitivity, specificity and positive predictive value of VIA, becoming a valid adjunctive screening test for cervical cancer in low resource settings.
