摘要
建立了一套基于反馈原理的,应用在毛细管破碎法微球制备装置中的压力自动控制系统。以灵敏压力传感器、单片机和高速电磁阀构成完整反馈环,结合模糊算法实现了对药液稳定高速喷射的自动控制。实验结果表明,在25℃时,以浓度为2%的海藻酸钠溶液制备微球,可以达到单喷头0.6L/h的流速。在适当的破碎频率下可以得到粒径偏差小于10%的微球。
Air pressure auto control system based on feedback theory is designed, which will be used in microcapsules preparation equipment. High speed electro valves, micro controller unit（MCU）and sensitive air pressure sensor which conform a complete feedback loop, together with fuzzy arithmetic, make the drug liquid spout steady going and high speed. Tested by experiment, in 25℃, using sodium alginate of 2% concentration for preparation of microcapsules, velocity of flow per spout is 0. 6L/h. Under proper vibration frequency, difference between diameter of microcapsules is less than 10%.
出处
《电子测量技术》
2006年第4期145-146,151,共3页
Electronic Measurement Technology
