摘要
本研究通过对炼焦作业工人的血硒、发硒、外周血淋巴细胞微核以及染色体畸变等生化、遗传指标的分析表明：炼焦作业工人血硒、发硒与对照比较未见明显异常（Ｐ＞０．０５），提示焦化作业工人肺癌的高发与机体内硒的缺乏无必然联系。焦炉工人外周血淋巴细胞微核率，染色体畸变率均增高，由此说明炼焦生产可产生某些致突变物质，这些物质可能与焦炉工人癌症高发有一定联系。故应加强对染色体畸变率明显增高人群的监护。
The biochemistry and genetic indexes of oven workers were measured.The results showed that serum carotene, blood Se and hair Se were not affected.It was suggested that lung cancer excess among the oven workers isn′t related to Se insufficiency.Lymphocyte transformation incidence,lymphocyte micronucleus incidence,lymphocyte chromosome aberration increased (P<0.01).The lymphocyte chromosome aberration incidence can be useful as a sensetive genotoxicity indicator for oven workers.
