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头孢呋辛序贯疗法治疗下呼吸道感染38例 被引量:2

Cefuroxine Sequential Therapy for Treatment of Lower Respiratory Tract Infection:Report of 38 Cases
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摘要 目的比较头孢呋辛序贯疗法和单纯静脉滴注疗法治疗下呼吸道感染的疗效。方法选择下呼吸道感染患者73例,随机分为两组,治疗组(38例)采用头孢呋辛钠(酯)序贯疗法,对照组(35例)采用单纯静脉滴注疗法,疗程均为5~10d。结果两组病情恢复指标(平均退热、咳喘消失、罗音消失、X线胸片恢复时间)均无明显差异;治疗组有效率为92.11%(35/38),细菌清除率为91.89%(34/37),对照组有效率为94.28%(33/35),细菌清除率为93.94%(31/33),两组间有效率、细菌清除率均无明显差异(P>0.05)。结论头孢呋辛序贯疗法治疗下呼吸道感染与单纯静脉滴注疗法疗效相似,但更经济、方便、安全。 Objective To compare the curative effect between cefuroxine sequential therapy and intravenous drip for the treatment of lower respiratory tract infection (LRTI). Methods Three patients with LRTI were divided into the treatment (38 cases) and the control (35 cases) groups. The patients in the treatment group received cofuroxime (Na^+ + Axetil) sequential therapy, and the patient in the control group received intravenous drip. The average treatment courses were all 5-10 d. Results The recovery signs of average defervescence, disappearance of cough and gasp, disappearance of rales and negative X-ray show for treatment and control group showed no obvious differences. The effective rate and bacterial clearance rate in the treatment group was 92.11% (35/38) and 91, 89% (34/37) respectively, and the control group was 94. 28% (33/35) and 93, 94% (31/33) respectively. There were no significant differences in both effective and bacterial clearance rates between two groups (P〉0.05). Conclusion There is similar curative effect for the treatment of LRTI by cefuroxine sequential therapy and intravenous drip, but sequential therapy is more economic, convenient and safer.
出处 《中国药业》 CAS 2006年第10期53-54,共2页 China Pharmaceuticals
关键词 头孢呋辛 头孢呋辛酯 序贯疗法 下呼吸道感染 治疗应用 cefuroxine cefuroxine axetil sequential therapy lower respiratory tract infection therapeutic use
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