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孟鲁司特联合激素治疗儿童哮喘 被引量:1

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摘要 目的观察白三烯受体拮抗剂孟鲁司特片联合吸入激素治疗儿童哮喘的疗效。方法对68例儿童哮喘患儿随即分为治疗组及对照组,治疗组在对照组的基础上加用顺尔宁,观察临床症状、PEF变异率及复发率。结果治疗组症状缓解时间(2.50±0.69)d,对照组(5.10±0.86)d,PEF变异率及复发率治疗组均较对照组改善明显。结论顺尔宁在治疗儿童哮喘中疗效确切、依从性好、服用方便、安全性高,值得在儿童哮喘治疗中推广。
作者 张国秀
出处 《医药论坛杂志》 2006年第17期81-81,83,共2页 Journal of Medical Forum
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  • 1Dent G, Ruhlmdnn E, Bodtake K, et al, Up-regulation of human eosinophilia leukotriene C4 generation through contact with bronchial ephithelial cell. Inflamm Res, 2000, 49 (5): 236-239. 被引量:1
  • 2Drazen JM. Effects of cysteiny leukotrienes on human airways. In Holgate S, Dahlen SE (ed). SRS-A to leukotrienes. Oxford:Blackwell Science, 1997: 189-201. 被引量:1
  • 3Laitinen LA, laitinen A, Haahtela T, et al. Leutriene E4 and granulocytic infiltration into asthmatic airways. Lancet, 1993, 341 :989-990. 被引量:1
  • 4Wang CG, Du T, Xu LJ, et al. Role of leukotriene D4 in allergeninduced in airway smooth muscle in the rat. Am Rev Respir Dis,1993, 148: 413-417. 被引量:1
  • 5Fregonese L, Silvestri M, Sabatini F, et al. Cysteinyl leukotrienes induce human eosinophil locomotion and adhesion molecule expression via a Cys-LTI receptor mediated mechanism. Clin Exp Allergy, 2002, 32: 745-750. 被引量:1
  • 6Braccioni F, Dorman SC, O′ byrne PM, et al. The effect of cysteinyl leukotrenes on growth of eosinophil proge from peripheral blood and bone marrow of atopic subjects. J Allergy Clin Immunol, 2002, 110:96-101. 被引量:1
  • 7Murray J, Ward c, O′ Flaberty JT, et al. Role of leukotrenes in the regulation of human granulecyte behaviour: dissociation between agonist-induced activation and retardation of apoptosis. Br J Pharmacol, 2003, 139:388-398. 被引量:1
  • 8Henderson WR Jr, Tang LO, Chu SJ, et al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med, 2002, 165:108-116. 被引量:1
  • 9Stelmach I, Jerzynska J, Kuna P. A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum ECP, sIL-2R, IL-4, and sICAM-1 in children with asthma. J Allergy Clin Immunol, 2002,109: 257-263. 被引量:1
  • 10Stelmach I, Grzelewski T, Stelmach W, et al. Effect of triamcinolone acetonide, montelukast, nedocromil sodium and formoterol on eosinophil blood counts, ECP serum levels and clinical progression of asthma in children. Pol Merkuriusz Lek, 2002,12:208-213. 被引量:1

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