摘要
目的:制备杏鲍菇多糖,寻找具有优良抗病毒、抗肿瘤活性的物质。方法:从杏鲍菇菌丝中分离、纯化出两种杏鲍菇多糖即A1和A2,并分别用杏鲍菇多糖A1和A2作为小鼠的免疫增强剂,观察其对抗肿瘤的影响;采用体外抗病毒试验测定了杏鲍菇多糖即A1和A2对I型单纯疱疹病HSV-1的活性。结果:制备了纯化杏鲍菇多糖;其在抗肿瘤的试验和抑制HSV-1活性的试验中给药组与对照组之间均有常显著的差异。结论:杏鲍菇多糖即A1和A2对小鼠产生较好的抗肿瘤作用;并有很强的抑制I型单纯疱疹病毒的活性。
AIM： The purpose is to prepare Exocellular Polysaccharides ,and to search for substance with high Antivirus activity. METHODS： Two polysaccharides namely A1 and A2 were isolated and purified from Submerged culture of Pleurotus eryngii ,The polysaccharide was used as immuno -potantiators, and its effects on tumors were observed. The activity of Exocellular Polysaccharides A1 and A2 were determinated by antiviral study in vitro on HSV - I. RESULTS ： There were very significant difference between the activities of Exocellular Polysaccharides on HSV - I and tumors. CONCLUSION Exocellular Polysaccharides produced effects on HSV - I and tumors.
出处
《莱阳农学院学报》
2006年第3期174-176,共3页
Journal of Laiyang Agricultural College
关键词
杏鲍菇多糖
抗病毒
抗肿瘤
exocellular polysaccharide
antivirus
anti - tumor
