摘要
WNT信号通路在肿瘤发生中有重要意义,它调节细胞生长、迁移和分化。由于它在众多人类肿瘤的发生中广泛活化,近年来这条通路在肿瘤研究方面受到很多关注。本文将介绍该通路与肿瘤发生的关系,以及目前该通路的研究在抗肿瘤治疗中的应用前景。
WNT signaling has been identified as one of the key signaling pathways in cancer, regulating cell growth, motility and differentiation. Because of its widespread activation in diverse human tumor diseases, the WNT pathway has gained considerable and growing interest in tumor research in recent years.
出处
《基础医学与临床》
CSCD
北大核心
2006年第8期922-925,共4页
Basic and Clinical Medicine
