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QT离散度与冠心病的关系 被引量:39

Analysis of the electrocardiographic QT interval dispersionin patients with coronany artery diseases
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摘要 根据132例患者冠脉造影(CAG)结果,结合临床诊断进行分组并分别从体表静息标准12导联心电图上测量得出QT间期离散度(QTd)与QTc间期离散度(Qtcd)。统计学处理结果显示:QTd、QTcd在冠脉正常组(C组)分别是22.7±19.7ms与28.0±15.9ms,冠脉病变组(B组)分别是36.4±16.6ms与41.0±17.5ms,与前组比较有显著差异(P<0.01)。急性心肌梗死组(A组)QTc、QTcd分别是64.8±25.4ms、73.1±29.4ms,与前两组比较均有明显差异(P<0.01)。结果显示:不但急性心肌梗死组QTd增大,而且冠脉病变组QTd也增大。故认为心肌缺血是QTd增大的重要原因之一,且可能与缺血产生速度和严重程度有关。 QT interval dispersion (QTd) defined as QTmaximum minus QTminnium, mea-sured from the 12 lead EDG reflects regional changes in ventricular recovery and is increased during theearly hours after myocardial infarction.To study the degree of ischemia-induced dispersion of ventric-ular recovery in CAD patients(pts.),we analyzrd changes in QTd in 132pts.all pts underwent percu-tanous coronary angiography(CAG).Of the 132 pts.46 had AMI,40 had coronary artery stenosisl(>50% in diameter,CA+)and 46 were considered normal or no significant lesions(CA-).Mean QTd in pts.with AMI.CA+ and CA-was 64.8+25.4ms,36.4+16.6ms,and 22.7+19.8ms respectively.There were signeficant difference in QTd between pts.with AMI and CA-(P<0.001),and between pts.with CA+ and CA-(P<0.0l).This study revealed that increased QTd occurs not only in pts.with AMI,but also in pts.withCA+, reflecting alterations in ventricular recovery due to ischemia.
出处 《临床心电学杂志》 1996年第4期156-158,共3页 Journal of Clinical Electrocardiology
关键词 QT离散度 冠心病 病理 QT interval dispersion coronary artecy disease
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