摘要
目的探讨气象因素变化对居民脑出血发病的影响。方法对连续5年间市区4家大医院1154例脑出血患者的发病时间特点进行分析,用构成比、方差分析和圆分布分别分析发病的月分布、季节差别和年度集中趋势,对8项月气象指标和2项候(每5天)气象指标及其变化对同期脑出血发病的影响进行单变量和多变量分析。结果(1)脑出血冬季高发,夏季低发;(2)脑出血发病有集中的趋势,平均角分别是12月、1月和2月(P<0·05);(3)单因素相关分析显示脑出血的月发病人数与3项温度指标均呈负相关,与3项气压指标均呈正相关;候发病例数只与候平均温度的候际差呈负相关(r=-0·35284,P<0·05);(4)多变量逐步回归分析显示脑出血与月平均气压、月平均相对湿度和月平均风速有关,脑出血的候发病例数只与候平均最低温度的候际差相关(P<0·05)。结论脑出血发病有明确的季节性,年度发病集中趋势是冬季的3个月份。脑出血发病与气温和气压突变有关,尤易于被降温诱发。多种气象因素相互协同或拮抗共同影响脑出血的发病。
Objective： To examine the influence of the changes of climatic factors on the occurrence of intracerebral hemorrhage （ICH） in residents. Methods： A total of 1 154 patients with ICH, whose characteristics of onset time of ICH in 4 general hospitals were analyzed for 5 consecutive years, The monthly distribution, seasonal variation and yearly concentrated trend of the onset of the disease were analyzed with proportion, variance analysis, and circular distribution. Univariate and multivariate analysis were performed for the influence of 8 monthly meteorological parameters and 2 five-day meteorological parameters and their changes on the onset of ICH at the same period. Results： （1） qhe incidence of ICH was higher in winter than that of in summer; （2） 1he incidence of ICH had a concentrated trend, the mean angles was December, January and February, respectively （P 〈0.05）; （3） Pearson＇s correlation analysis showed that the monthly incidence of ICH was all negatively correlated with 3 temperature parameters, and positively correlated with 3 barometric parameters; five-day incidence was only negatively correlated with the inter-five-day differences of the five-day average temperature （r = -0. 352 84, P 〈0.05）; and （4） the multiple stepwise regression analysis showed that ICH was associated with the monthly average barometric pressure, monthly average relative humidity and monthly average wind speed, and that the five-day incidence of ICH was only associated the with the inter-fiveday differences of the five-day average lowest temperature （P 〈0.05）. Conclusions： The onset of ICH has obvious seasonal variation, and its concentrated trend of annual episode is the 3- month winter period, The onset of ICH is associated with sudden changes of temperature and barometric pressure, especially induced by dropping in temperature, The mutual synergy of multiple climatic factors or antagonism may commonly influence the onset of ICH.
出处
《国际脑血管病杂志》
2006年第7期500-505,共6页
International Journal of Cerebrovascular Diseases
基金
青岛市卫生局科技攻关项目资助课题(2000-WS01)
关键词
气象因素
脑出血
climatic factor
intracerebral hemorrhage
