摘要
目的：观察外侧半月板切除术后膝关节周围骨密度的变化及其影响因素．方法：选择术后患者128例，根据术后时间分为：0—1a组，2～4a组，5～10a组和11～17a组，对照组为对应健侧；根据性别、手术时年龄和体质量各设：男性组，女性组；≤40岁组，〉40岁组；≤75kg组，〉75kg组；应用双能X线骨密度仪测量膝关节周围6个目的区（ROI）骨密度，并进行性别、年龄和体质量与骨密度的线性相关分析．结果：0～1a组6区骨密度下降，R1-R4下降显著分别为0．93±0．30，0．91±0．21，1．25±0．36和1．30±0．51（P〈0．01）；2—4a组R1～R4骨密度下降，而R5，R6骨密度增加，其中以R1，R3变化显著，分别为0．93±0．22和1．28±0．08（P〈0．01）；术后5—10a组除R2骨密度下降外，其余骨密度增加，以外侧ROI骨密度增加显著，分别为0．95±0．12，1．20±0．19及1．25±0．18（P〈0．05）；术后11～17a组R1，R3骨密度下降分别为：0．93±0．20，1．19±0．18，与对照组比较差异有显著的统计学意义（P〈0．05）．结论：外侧半月板切除术后膝关节周围发生适应性骨重构是多种因素作用的结果．
AIM： To investigate the change of bone mineral density around the knee joint and the influential factors for the change after lateral meniscectomy （LMT）. METHODS： A total of 128 patients who had undergone LMT were divided into 0-1 year group, 2-4 year group, 5-10 year group and 11-17 year group according to the time after LMT; tfealthy contralateral leg was assigned to control groups respectively. According to sex , operated age and weight, they were also divided into men group, women group ; ≤40 years age, 〉40 years age ; ≤75 kg, 〉75 kg. The bone mineral density in the 6 regions of interest （ROI） were measured using dual energy X-ray absorptiometry, and the sex, age, weight and the bone mineral density were analyzed by linear correlation. RESULTS：Bone mineral density in the 6 ROI were all decreased in 0-1 year group. They were decreased in R1-R4 significantly to 0.93 ±0.30, 0.91 ±0.21, 1.25 ±0.36 and 1.30 ±0. 51 （P 〈 0.01）, respectively. In 2-4 year group , bone mineral density in R1- R4 were decreased, while it in R5 and R6 was increased. The value of changes in R1 and R3 were significant as 0.93 ±0.22 and 1.28 ±0.08 （P〈0.01） . Except that bone mineral density in R2 was decreased, the values in the other regions were increased. The bone mineral density on lateral side increased significantly to 0.95 ±0.12, 1.20 ±0.19 and 1.25 ± 0.18 （P〈0.05）. In 11-17 year group, bone mineral density in R1 and R3 was decreased as 0.93 ±0.20, 1.19 ±0.18. There was a significant difference in comparison with control groups respectively （P 〈0.05）. CONCLUSION： Adaptive bone remodeling around the knee after LMT may result from many factors.
出处
《第四军医大学学报》
北大核心
2006年第16期1489-1492,共4页
Journal of the Fourth Military Medical University
基金
河北省科技攻关计划性指导课题(042761375)
关键词
外侧半月板切除术
骨密度
膝关节
影响因素
lateral meniscectomy
bone mineral density
joint knee
influential factor
