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胰岛素上调3T3-L1细胞apelin基因表达的初步观察 被引量:7

Insulin up-regulates expression of apelin gene in 3T3-L1 cells:a preliminary observation
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摘要 Northern印迹法证实apelin在分离的小鼠脂肪细胞上有表达,其表达量随3T3-L1细胞分化而渐增。胰岛素上调3T3-L1脂肪细胞apelin的表达,提示脂肪细胞apelin的表达可能与肥胖、胰岛素抵抗、高血压相关。 Expression of apelin mRNA in the isolated mouse adipocytes was confirmed by Northern blot. The level of apelin mRNA increased during stage of differentiation of 3T3-L1 cells. Insulin up-regulated the apelin expression in 3T3-L1 adipocytes, suggesting that apelin expression in adipocyte may correlate with obesity, insulin resistance and hypertension.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2006年第4期384-385,共2页 Chinese Journal of Endocrinology and Metabolism
关键词 APELIN 脂细胞 3T3-L1细胞 胰岛素 Apelin Adipocytes 3T3-L1 cell Insulin
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参考文献11

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