摘要
目的介绍感咳清颗粒的制备、薄层鉴别方法并预测其保质期。方法以薄荷、黄芩、防风等为原料制备感咳清颗粒剂;参照《中国药典》的方法对该制剂的主药进行薄层定性鉴别;用加速实验法以黄芩苷含量为指标预测了该制剂的稳定性。结果感咳清颗粒定性鉴别的专属性强;高温加速实验法测得常温下复方制剂以黄芩苷含量为指标的保质期为2年半。结论该制剂质量稳定可控。
Aim To introduce the preparation and TLC identification methods of GANKEQING granules and to determine the guarantee period. Methods Gan Ke Qin granules was prepared using Herba Mentha , Radix Scutellariae , Radix Saposhnikoviae and so on. It＇s major components were identified by TLC according to the methods of CHINESE PHAMACOPOEIA; Drug stability was estimated by determining the content of baicalin with the method of accelerated high temperature experimentation. Results the qualitative identification method was specific and the guarantee period evaluated by the accelerated high temperature experimentation was 2.5 years. Conclusion The quality of GanKeQing granules is controllable and stable.
出处
《解放军药学学报》
CAS
2006年第4期312-314,共3页
Pharmaceutical Journal of Chinese People's Liberation Army
关键词
感咳清颗粒
薄层鉴别
稳定性研究
GanKeQing granules
TLC identification
Stability research
