摘要
以草酸二乙酯为原料,经氨解,肼解,环合,醇解,而制得1,2,4-三唑-3-羧酸甲酯。该合成工艺具有步骤少,条件温和,操作简便,污染少,产率较高等优点。
Starting from oxalic acid diethyl ester, the synthesis of methyl 1,2,4-triazole-3-carboxylate was improved by aminolysis, hydrazinolysis, cyclization, alcoholysis. The improved synthesis had several advantages such as few procedures, mild reaction conditions easy operation, low contaminstion and high yield of product.
出处
《化学试剂》
CAS
CSCD
北大核心
2006年第8期503-504,共2页
Chemical Reagents
关键词
草酸二乙酯
环合
醇解
1
2
4-三唑-3-羧酸甲酯
工艺改进
oxalic acid diethyl ester
cyclization
hydrazinolysis
alcoholysis
methyl 1,2,4-triasole-3-carboxylate
improved method
